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July 11th, 2003 Octapharma sponsors DIC / sepsis web site Multiple organ failure induced by sepsis or disseminated intravascular coagulation (DIC) is the leading cause of death in intensive care units. It occurs in approximately one hospital patient in every 1000 and may result in critical illness or death as a result of failure of one or multiple organs.  During severe sepsis a generalised activation of the haemostatic system occurs and this leads to the formation of fibrin clots in the microvasculature. This condition is known as DIC. DIC can also be provoked by other mechanisms and may, by itself cause multiple organ dysfunction syndrome (MODS).Damage to organs is the result of uncontrolled, systemic activation of the haemostatic system and inflammatory processes. The terminology used can sometimes be confusing. The terms ‘disseminated intravascular coagulation’, ‘systemic inflammatory response syndrome’ (SIRS) and multiple organ deficiency syndrome (MODS) cover a number of closely related disorders and are often used indiscriminately. DIC and SIRS, however, describe pathophysiological conditions, while MODS describes the results of the processes.
The site is designed for physicians who encounter disseminated intravascular coagulation but also includes an area for general public access which includes educational information on DIC. The restricted membership area of the site provides registered physicians with a unique opportunity to interact with independent, worldwide experts in the area of DIC. These experts include the Editor-in-Chief Professor Jørn Dalsgaard Nielsen (Denmark) and Associate Editors Professor Lars Heslet (Denmark), Associate Professor Bengt Gårdlund (Sweden), Professor Marcel Levi (The Netherlands), Dr Richard Strauss (Germany) and Dr Johannes Hoffmann (Germany). The contents of this website are updated regularly and reviewed by the panel of experts. Currently, the website contains specific sections on:
Editor-in-chief Professor Jørn Dalsgaard Nielsen, states “We hope that members of this website will share their knowledge with colleagues and through dialogue get new insights into the complexity of DIC & sepsis. Comprehension of the pathophysiological conditions surrounding MODS is essential if we are being able to move away from the symptomatic treatment of organ dysfunction and towards more effective therapeutic initiatives.”If you would like to register as a member of DICsepsis.org please click here (by clicking this link you will leave the www.octapharma.com site).
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