Mario, 21 years

Mario was born with agammaglobulinaemia, the most common primary immune deficiency (PID). His blood contains no B-lymphocytes, and hence his body has none of the antibodies (immunoglobulins) it needs to fight diseases.
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Siegrid, 66 years

Siegrid was diagnosed with common variable immunodeficiency (CVID) when she was 47 years old. Her blood lacks the capacity to produce antibodies, which leads to frequent bacterial infections.
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Gleb, 9 years

Several of Gleb's family members have haemophilia. Gleb was diagnosed with severe haemophilia A when he was only 7 months old, and severe haemophilia A with inhibitors when he was 14 months old. Spontaneous haemorrhages occured as a result of even the lightest physical activity - making life very difficult for his entire family.
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Georgy, 5 years

Georgy was diagnosed with severe haemophilia A when he was only one year old. There are carriers in the family and one of Georgy’s uncles also has the condition. Later, when he was almost three, Georgy was found to have factor VIII inhibitors after he was treated unsuccessfully with one recombinant and several plasma-derived factor VIII concentrates.
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Jack, 3 years

Jack was diagnosed with severe haemophilia A at birth and despite high dose ITI treatment with recombinant factor VIII, his inhibitor level continued to rise. Jack was switched to octanate® in April 2009 and his inhibitor level has been steadily falling ever since.
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