Human Antithrombin III Concentrate

Atenativ® is a human antithrombin III concentrate (AT III) for the treatment of patients with congenital antithrombin deficiency.


Treatment of patients with congenital antithrombin deficiency:

  • Prophylaxis for the prevention of deep vein thrombosis and thromboembolism in clinical risk situations (especially in surgery, pregnancy and childbirth), in combination with heparin, if indicated.

  • Prevention of the progression of deep venous thrombosis and thromboembolism associated with heparin as indicated.


Atenativ® is presented in vials containing 500 IU and 1000 IU of human antithrombin III as lyophilised powder for infusion. After reconstitution with 10 mL water for injection (WFI), the solution provides 50 IU/mL or 100 IU/mL of human antithrombin III.

Store in the refrigerator (2-8 °C) Keep the vials in the outer carton in order to protect from light. The shelf life is three years.


1. Atenativ® - Summary of product characteristics (Switzerland)

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