Kawasaki Disease misdiagnosis
KD was considered the leading cause of acquired heart disease in children for many years. However, during the COVID-19 pandemic, a new syndrome appeared: multisystem inflammatory syndrome in children (MIS-C).
At the same time, there was a decrease in the incidence of KD, possibly due to strategies to combat the pandemic, such as masking, social distancing and lock-downs. Some of this decrease may be related to the misclassification of KD patients as having MIS-C, or it could be due to reduced exposure to possible infectious/environmental triggers.
Given the clinical overlap, there is growing interest in the immunological mechanisms underlying both diseases, as insights into one condition may shed light on the diagnosis, treatment and long-term management of the other.8