Human Fibrinogen Concentrate

During blood coagulation, fibrinogen (coagulation factor I) is converted into fibrin by the serine protease thrombin (coagulation factor IIa).

Fibrinogen has various applications in pharmaceutical and biotechnological manufacturing. It can be used as a coating on medical devices, and in wound healing. Combined with thrombin, Fibrinogen can be applied to a collagen patch for use as a topical hemostatic agent. These two agents are used to induce rapid hemostasis and tissue sealing following a variety of indications including thoracic, plastic, pediatric, hepatic and minimally invasive surgery.1

References: 1) Brinkman JM (2016) Anticoagulation Therapy, chapter 5. DOI: 10.5772/64304